Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Reexamination Certificate
2007-01-30
2007-01-30
Gitomer, Ralph (Department: 1657)
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
C435S014000
Reexamination Certificate
active
10782290
ABSTRACT:
The invention concerns an arrangement for determining the concentration of glucose in a tissue fluid. In the microdialysis technology used for this purpose, perfusate-containing glucose is transported in intermittent delivery pulses through a microdialysis probe inserted into the tissue fluid and dialysate obtained in this process is passed to a measuring cell to record the glucose content. In order to achieve an exact determination of glucose even with a reduced dialysis period, it is proposed that the starting content of glucose in the perfusate is adapted to the glucose content of the tissue fluid by means of a control device in accordance with a command variable derived from the measurement signals of the measuring cell. When the control deviation is negligible the momentary starting content of glucose in the perfusate can be determined as a measure for the glucose content of the tissue fluid.
REFERENCES:
patent: 5615671 (1997-04-01), Schoonen et al.
patent: 5640954 (1997-06-01), Pfeiffer et al.
patent: 6013029 (2000-01-01), Korf et al.
patent: 6091976 (2000-07-01), Pfeiffer et al.
patent: 6434409 (2002-08-01), Pfeiffer et al.
patent: 6591126 (2003-07-01), Roeper et al.
patent: 6852500 (2005-02-01), Hoss et al.
patent: 6925393 (2005-08-01), Kalatz et al.
patent: 41 30 742 (1993-03-01), None
patent: 44 26 694 (1996-02-01), None
patent: 44 01 400 (1997-06-01), None
patent: WO 97/42868 (1997-11-01), None
patent: WO 97/42868 (1997-11-01), None
Dempsey et al. (1997). In vitro optimisation of a microdialysis system with potential for on-line monitoring of lactate and glucose in biological samples. Analyst 122 (185-189), pp. 185-189.
Fussgaenger Rolf
Gessler Ralf
Hoss Udo
Pfleiderer Hans-Joerg
Zieten Hans-Ulrich
Gitomer Ralph
Roche Diagnostics GmbH
Subrananiam Sujatha
Woodburn Jill L.
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