Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing
Patent
1996-05-15
1999-01-12
Beisner, William H.
Chemistry: molecular biology and microbiology
Apparatus
Including measuring or testing
4352862, 4352875, 4352881, 4352887, C12M 134
Patent
active
058587691
ABSTRACT:
An apparatus and method for mixing/agitating microorganism culture bottles includes a wheel in which culture bottles are placed, with the wheel being set at an angle from vertical so that bottles are not inverted during rotation. A sensor such as a florescence or colorimetric sensor for carbon dioxide is disposed along the flat bottom surface of each of the bottles. Once during each revolution the bottles pass across a photodiode/light emitting diode pair (for a calorimetric system). A sensor transmits light emitted by the LED to the photodiode. At the same instant, an infrared reflective objective sensor, emitting on a digital rotary encoder, determines the bottle number. The change in sensor transmittance is directly related to cell growth so that bottles positive for growth can be detected by suitable software.
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DiGuiseppi James L.
Thorpe Thurman C.
Akzo Nobel N.V.
Beisner William H.
Muir Gregory R.
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