Combinatorial chemistry technology: method – library – apparatus – Method of creating a library – Liquid-phase synthesis or particular method of cleavage from...
Reexamination Certificate
2003-01-13
2009-06-09
Schultz, J D (Department: 1639)
Combinatorial chemistry technology: method, library, apparatus
Method of creating a library
Liquid-phase synthesis or particular method of cleavage from...
C435S006120, C506S023000, C506S033000
Reexamination Certificate
active
07544638
ABSTRACT:
This invention provides method and apparatus for performing chemical and biochemical reactions in solution using in situ generated photo-products as reagent or co-reagent. In particular, the present invention provides methods and devices for generating a photogenerated reaction in solution on a substrate comprising generating a light beam using an optical device system comprising a light source and a computer-controlled spatial optical modulator comprising a digital micromirror device and using the spatial optical modulator to direct light to fluidly isolated reaction sites under conditions such that a photogenerated reaction takes place. The method and apparatus of the present invention have applications in parallel synthesis of molecular sequence arrays on solid surfaces.
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McGall, G
Gao Xiaolian
Gulari Erdogan
Zhou Xiaochuan
Casimir Jones S.C.
Lundgren Jeffrey S.
Schultz J D
The Regents of the University of Michigan
University of Houston
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