Device for carrying out optical measurements in turbid media

Details Device for carrying out optical measurements in turbid media Device for carrying out optical measurements in turbid media

1996-03-20

1998-03-03

Casler, Brian L.

Surgery

Truss

Pad

128664, 128665, 356432, 250330, A61B 505

Patent

active

057224064

ABSTRACT:
A device for localizing an object 118 in a turbid medium (111), includes a laser (100) which is used for generating amplitude modulated light that is conducted into a turbid media (111), and a detection unit (107) for measuring the amplitude-modulated light emanating from the turbid media. A signal processing unit (109) measures a phase and amplitude from the detector signal (115). Based on the insight that the accuracy of the measured phase is influenced by higher harmonics present in the detector signal (115), the accuracy of the phase detection is improved by reducing such higher harmonics. This is achieved by reducing the higher harmonics in the amplitude modulated light from the laser (100) by utilizing a two-mode laser.

REFERENCES:
patent: 5416582 (1995-05-01), Knutson et al.
patent: 5424843 (1995-06-01), Tromberg et al.
patent: 5497769 (1996-03-01), Gratton et al.
patent: 5582168 (1996-12-01), Samuels et al.
patent: 5625458 (1997-04-01), Alfano et al.
"Digital Parallel Acquisition in Frequency Domain Fluorimetry" B. Feddersen et al, Rev. Sci. Instrum. 60 (9) Sep. 1989, pp. 2929-2936.

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