Device for capturing beads and method and apparatus for...

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

11195701

ABSTRACT:
Beads having diameters of several tens of micrometers to several millimeters and immobilized with biomolecules are captured by one kind of bead capturing nozzle one by one without fail. Using a bead holding plate having a plurality of wells each of which holds a plurality of the beads and a solution, a vibration generator mounted with a stage to attach the bead holding plate, and a bead capturing nozzle for bead capture connected to a suction pump, only a single bead is captured at the tip of the bead capturing nozzle by inserting the nozzle having an inner diameter smaller than the beads and a negative pressure inside created by the pump into the solution to allow the nozzle to come in contact with the beads in the well, applying a vibration to the bead holding plate by the vibration generator, and withdrawing the bead capturing nozzle into the air.

REFERENCES:
patent: 3941565 (1976-03-01), Schwartz
patent: 5935859 (1999-08-01), Elliott et al.
patent: 6023540 (2000-02-01), Walt et al.
patent: 6255116 (2001-07-01), Leber et al.
patent: 2003/0198575 (2003-10-01), Noda et al.
patent: 2004/0265181 (2004-12-01), Noda et al.
patent: 1 522 340 (2004-09-01), None
patent: 11-243997 (1998-03-01), None
patent: 2000-346842 (2000-04-01), None
patent: 2003-315336 (2002-04-01), None
patent: 2005-017224 (2003-06-01), None
H. Noda et al., “Automated Bead Alignment Apparatus Using a Single Bead Capturing Technique for Fabrication of a Miniaturized Bead-Based DNA Probe Array”, Anal. Chem., vol. 75, No. 13 (Jul. 1, 2003), pp. 3250-3255.
S. Fodor et al., “Light-Directed,Spatially Addressable Parallel Chemical Synthesis”, Science, vol. 251 (Feb. 15, 1991), pp. 767-773.
M. Schena et al., “Quantitative Monitoring of Gene Expression Patterns with a Complementary DNA Microarray”, Science, vol. 270 (Oct. 20, 1995), pp. 467-470.
T. Okamoto et al., “Microarray Fabrication with Covalent Attachment of DNA Using Bubble Jet Technology”, Nature Biotechnology, vol. 18 (Apr. 2000), pp. 438-441.
R. J. Fulton et al., “Advanced Multiplexed Analysis with the FlowMetrix™ System”, Clinical Chemistry, vol. 43, No. 9 (1997), pp. 1749-1756.
Y. Kohara et al., “DNA Probes on Beads Arrayed in a Capillary, ‘Bead-array’, Exhibited High Hybridization Performance”, Nucleic Acids Research (2002), vol. 30, No. 16, pp. 1-7.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Device for capturing beads and method and apparatus for... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Device for capturing beads and method and apparatus for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Device for capturing beads and method and apparatus for... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3905918

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.