Device for administering an active agent to the skin or mucosa

Details Device for administering an active agent to the skin or mucosa Device for administering an active agent to the skin or mucosa

1989-03-21

1991-01-08

Cashion, Jr., Merrell C.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

424449, 424447, 424434, A61F 1302

Patent

active

049833952

ABSTRACT:
A transdermal drug delivery device comprising a drug formulation-containing reservoir defined by a backing layer and a drug-permeable membrane layer, a peelable inner liner that underlies the reservoir and a portion of the backing/membrane outwardly of the reservoir periphery, an adhesive layer that underlies the inner liner and outwardly extending portions of the membrane/backing layers, and a peelable release liner layer that underlies the adhesive layer with a first permanent heat seal between the backing and the membrane about the perimeter of the reservoir and another concentric peelable (impermanent) heat seal between the membrane and the inner liner positioned underlying and at a radius not less than the first permanent heat seal, the heat seals and peelable barrier layer providing barriers that isolate the drug formulation from the adhesive.

REFERENCES:
patent: 4849224 (1989-07-01), Chang et al.

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