Device for administering an active agent to the skin or mucosa

Details Device for administering an active agent to the skin or mucosa Device for administering an active agent to the skin or mucosa

1987-11-12

1989-07-18

Swisher, Nancy A. B.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424448, 424449, A61F 1300

Patent

active

048492248

ABSTRACT:
A transdermal drug delivery device comprising a drug formulation-containing reservoir defined by a backing layer and a drug-permeable membrane layer, a ring-shaped layer made of an adhesive that is incompatible with one or more components of the drug formulation that is peripheral to the reservoir outwardly of the membrane layer and a peelable liner layer that underlies at least the membrane layer with a first heat seal between the backing and the membrane about the perimeter of the reservoir and another concentric heat seal between the backing and the release liner positioned outwardly of the first heat seal, the heat seals providing barriers that isolate the drug formulation from the adhesive.

REFERENCES:
patent: 4560553 (1985-12-01), Zupan
patent: 4568343 (1986-02-01), Leeper et al.
patent: 4573996 (1986-03-01), Kwiatek et al.
patent: 4637930 (1987-01-01), Konno et al.
patent: 4655767 (1987-04-01), Woodward et al.
patent: 4687481 (1987-08-01), Nuwayser
patent: 4690683 (1987-09-01), Chien et al.
patent: 4695277 (1987-09-01), Lauk
patent: 4704119 (1987-11-01), Shaw et al.
patent: 4710191 (1987-12-01), Kwiatek et al.
patent: 4747841 (1988-05-01), Kuratomi et al.
patent: 4764379 (1988-08-01), Sanders et al.

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