Chemistry: molecular biology and microbiology – Apparatus
Reexamination Certificate
2006-01-13
2008-08-12
Saucier, Sandra (Department: 1651)
Chemistry: molecular biology and microbiology
Apparatus
C435S030000, C435S034000, C435S177000, C435S180000, C435S243000, C435S252100, C435S252400, C435S253600, C435S254100, C435S255100, C435S256800, C435S287100, C435S289100, C435S395000, C435S402000, C435S482000
Reexamination Certificate
active
07410791
ABSTRACT:
The invention provides a device for adhering cells in a specific and predetermined position, and associated methods. The device includes a plate defining a surface and a plurality of cytophilic islands that adhere cells, isolated by cytophobic regions to which cells do not adhere, contiguous with the cytophilic islands. The islands or the regions or both may be formed of a self-assembled monolayer (SAM).
REFERENCES:
patent: 5776748 (1998-07-01), Singhvi et al.
patent: 5976826 (1999-11-01), Singhvi et al.
patent: 6368838 (2002-04-01), Singhvi et al.
patent: 7067306 (2006-06-01), Singhvi et al.
Ingber Donald E.
Kumar Amit
Lopez Gabriel P.
Singhvi Rahul
Stephanopoulos Gregory
Children's Medical Center Corporation
Massachusetts Institute of Technology
President and Fellows of Harvard College
Saucier Sandra
Ware Deborah K.
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