Device and process unit for providing a hybridization chamber

Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing

Reexamination Certificate

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C435S286700, C435S288500, C435S293100

Reexamination Certificate

active

07618812

ABSTRACT:
A device provides a hybridization chamber for hybridizing nucleic acid samples, proteins or tissue sections on a slide, and is an essentially rectangular body movable opposite the slide. The device includes a surface, lines for supplying and/or removing media, a specimen supply line and an agitating device. The agitation device includes at least one membrane which separates a pressure chamer to be fillable with a pressure fluid via one of the lines, from at least one agitation chamber connected via an agitation line to the hybridization chamber. The lines are continuously open so the media therein can permanently flow unhindered. Four such devices can be combined into a process unit for providing a hybridization chamber. Such unit is pivotable around an axis and has a holder with four seats, which is lockable in relation to a baseplate, one device being insertable into each one of the seats.

REFERENCES:
patent: 5958760 (1999-09-01), Freeman
patent: 6238910 (2001-05-01), Custance et al.
patent: 6432696 (2002-08-01), Custance et al.
patent: 6946287 (2005-09-01), Streit et al.
patent: 0695941 (1996-02-01), None
patent: 0891811 (1999-01-01), None
patent: WO 00/09650 (2000-02-01), None
patent: WO 00/54874 (2000-09-01), None
patent: WO 02/41994 (2002-05-01), None
Anders Olsson, “Valve-less Diffuser Micropumps,” Trita-Ila, Institutionen for Elektrisk Matteknik Kungl. Teknisa Hogskolan, SE. Nr. 9803 1998.

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