Refrigeration – Processes – Treating an article
Patent
1996-09-06
1999-02-23
Bennett, Henry
Refrigeration
Processes
Treating an article
62 64, 62 65, 62374, 62380, F25D 1306
Patent
active
058732543
ABSTRACT:
A device for controlled freezing and warming of a biological sample, and freezing and thawing protocols for which the device is well suited. The device establishes a laterally varying thermal gradient and provides a mechanism for moving the sample along the thermal gradient at a controlled rate of speed. The sample is moved along the thermal gradient at a rate of speed that provides a variable cooling rate or a variable warming rate in accordance with the appropriate protocol. The device also allows continuous seeding of the sample through the freezing process at the exact freezing point of the solution. Real time monitoring and video imaging of the freezing process enable fine tuning of the thermodynamic parameters for improved control.
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Bennett Henry
Friedman Mark M.
Interface Multigrad Technology
Wilson Pamela A.
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