Device and method of measuring the viscosity and/or visco-elasti

Measuring and testing – Liquid analysis or analysis of the suspension of solids in a... – Viscosity

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G01N 1108

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active

045663149

ABSTRACT:
A method and device for handling a fluid to accurately measure the viscosity and/or visco-elasticity of the fluid. More particularly, the method and device hereof is adapted for reliable calibration and filling with a subject fluid, such as blood, enabling accurate measurement even when only a small amount of the subject fluid is available for analysis. Broadly speaking, the device includes a measuring chamber filled with a standard fluid, a coupling chamber filled with a coupling fluid, a flexible diaphragm separating the chambers, and a measuring tube suspended in a downward direction from the coupling chamber. The measuring chamber includes a pressure and flow generating plunger and a pressure sensor; a flow sensor is operably coupled to the measuring chamber. Preferably, the measuring tube is filled with subject fluid by first drawing an air bubble into the tube and then drawing the subject fluid into the tube to completely fill the tube. The air bubble serves to separate the subject fluid from the coupling fluid. After the tube is filled, a fluid interface between the coupling fluid and subject fluid is formed with the air bubble rising upwardly through the coupling fluid to the top of the coupling chamber.

REFERENCES:
patent: 2011862 (1935-08-01), Konheim et al.
G. B. Thurston, "Viscoelasticity of Human Blood", Biophysical Journal, vol. 12, (1972), pp. 1205-1217.
R. Zitny et al., "Continuous Recording of Flow Curves on a Capillary Rheometer Using a New Pressure Transmission Element", Jrnl. of Physics, E; Scientific Instruments, vol. 8, No. 3, (1975).

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