Device and method for the rapid qualitative and quantitative det

Details Device and method for the rapid qualitative and quantitative det Device and method for the rapid qualitative and quantitative det

1988-07-18

1993-06-08

Saunders, David

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

422 56, 422 57, 422 58, 435 792, 435 793, 435805, 435969, 435970, 435971, 436170, 436805, 436810, G01N 3353, G01N 33558

Patent

active

052179052

ABSTRACT:
A device for the rapid qualitative and quantitative determination of the presence of a reactive ligand in a fluid.
This device comprises a first reaction zone in which there is an at least temporarily impermeable membrane designed to receive a sample of test fluid and to be associated with at least one labeled reagent; a second reaction zone which is bounded on the one hand by the said membrane and on the other by a second at least temporarily impermeable membrane comprising a solid phase containing a reference reagent; and a third reaction zone which contains means for developing the reaction.
A method for the rapid qualitative and quantitative determination of the presence of a reactive ligand in a fluid.
Applications to the detection of the presence, in a biological fluid, of antibodies or antigens in particular.

REFERENCES:
patent: 4446232 (1984-05-01), Liotta
patent: 4522786 (1985-06-01), Ebersole
patent: 4668619 (1987-05-01), Greenquist et al.
patent: 4743542 (1988-05-01), Graham, Jr. et al.
patent: 4791055 (1988-12-01), Boguzlash et al.
patent: 4803170 (1989-02-01), Stanton et al.

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