Device and method for the detection of particles

Optics: measuring and testing – Document pattern analysis or verification

Reexamination Certificate

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Reexamination Certificate

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08040494

ABSTRACT:
The present invention relates to devices and methods for the qualitative and/or quantitative detection of particles. In particular, the invention relates to devices for the detection of particles, comprising a reaction chamber formed within a chamber body between a first surface and a second surface, wherein the second surface is located opposite to the first surface, and one or more displacers, wherein the distance between the first surface and the second surface is variable via the one or more displacers at least in one or more parts of the surface area of the first surface and/or the second surface. The invention also relates to corresponding methods for the detection of particles, comprising positioning a sample supposed to comprise one or more species of particles to be detected in a reaction chamber, displacing at least a part of the sample within the reaction chamber via the one or more displacers; and detecting/determining a value indicative for the presence and/or number of one or more species of particles.

REFERENCES:
patent: 0 891 811 (1999-01-01), None
patent: 0891811 (1999-01-01), None
patent: 2 803 225 (2001-07-01), None
patent: WO 03/015923 (2003-02-01), None
patent: WO 03/022435 (2003-03-01), None
Dongeun Huh et al: “Topical Review” Physiological Measurement, Institute of Physics Publishing, Bristol, GB, vol. 26, No. 3, Jun. 1, 2005, pp. R73-R98.
Dongeun, Huh, et al., “Microfluidics for flow cytometric analysis of cells and particles,”Institute of Physics Publishing Physiol. Meas. (2005) vol. 26 pp. R73-R98.

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