Device and method for the detection of an analyte utilizing...

Chemistry: molecular biology and microbiology – Apparatus – Including measuring or testing

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C422S051000, C422S051000, C422S051000, C422S051000, C435S006120, C435S007200, C435S007210, C435S287900, C435S288400, C435S288500, C435S288700, C435S810000, C436S164000, C436S514000, C436S518000, C436S524000, C436S525000, C436S526000, C436S527000, C436S531000, C436S533000, C436S534000, C436S805000, C436S806000, C436S807000, C436S809000

Reexamination Certificate

active

07005292

ABSTRACT:
Disclosed are devices for detecting the presence of a preselected analyte in a fluid sample. The devices comprise a substrate microfabricated to define a sample inlet port, and a mesoscale flow system that includes a sample flow channel extending from the inlet port. The mesoscale flow system further includes an analyte detection region in fluid communication with the flow channel comprised of a binding moiety for specifically binding the analyte. The detection region is constructed with a mesoscale dimension sufficiently small to enhance binding of the binding moiety and the analyte. The binding moiety may be immobilized in the detection region. The mesoscale detection systems of the invention may be used in a wide range of applications, including the detection of cells or macromolecules, or for monitoring reactions or cell culture growth.

REFERENCES:
patent: 4233029 (1980-11-01), Columbus
patent: 4302313 (1981-11-01), Columbus
patent: 4618476 (1986-10-01), Columbus
patent: 4906439 (1990-03-01), Grenner
patent: 4908112 (1990-03-01), Pace
patent: 4911782 (1990-03-01), Brown
patent: 4963498 (1990-10-01), Hillman
patent: 5135720 (1992-08-01), Uchida
patent: 5147606 (1992-09-01), Charlton
patent: 5296375 (1994-03-01), Kricka et al.
patent: 5304487 (1994-04-01), Wilding et al.
patent: 5427946 (1995-06-01), Kricka et al.
patent: 5486335 (1996-01-01), Wilding et al.
patent: 5498392 (1996-03-01), Wilding et al.
patent: 5587128 (1996-12-01), Wilding et al.
patent: 5637469 (1997-06-01), Wilding et al.
patent: 5726026 (1998-03-01), Wilding et al.
patent: 5744366 (1998-04-01), Kricka et al.
patent: 5866345 (1999-02-01), Wilding et al.
patent: 5955029 (1999-09-01), Wilding et al.
patent: 6551841 (2003-04-01), Wilding et al.
patent: 6660517 (2003-12-01), Wilding et al.
patent: 3915920 (1990-11-01), None
patent: 0 320 308 (1989-06-01), None
patent: 0 439 182 (1991-07-01), None
patent: 2191110 (1987-12-01), None
patent: WO 91/13338 (1991-09-01), None
patent: 91/16966 (1991-11-01), None
patent: WO 91/16966 (1991-11-01), None
Anderson,Nature, 355:379 (1992).
Angell, et al.,Scientific American, 248:44-55 (1983).
Appenzeller,Science, 254:1300-1342 (1991).
Barany,Proc. Natl. Acad. Sci, 88:189-192 (1991).
Brown, “Development of a Stopped-Flow Cytometer, ”NSF Grant No. ISI 87-60730.
Brunette,Exper. Cell Res., 167: 203-217 (1986).
Brunette,Exper. Cell Res., 164: 11-26 (1986).
Columbus et al.,Clin. Chem., 33:1531-1537 (1987).
DeLuca et al.,Arch. Biochem. Biophys., 255:285-292 (1983).
Dessy,Cheometrics and Intelligent Laboratory Systems, 8:311 (1990) Abstract..
Esashi et al., “Integrated Flow Control Systems Fabricated on a Silicon Wafer,” Proceedings, Electrochemical Society Conference, HI (Oct. 18-23,1987), Electrochemical Society, Pennington, NJ, pp. 31-38B, 1987.
Fromherz et al.,Biochemica et Biophysica Acta, 1062:103-107 (1991).
Goin et al.,Clin. Chem., 32:1655-1659 (1986).
Haller in:Solid Phase Biochemistry, W.H. Scouten, Ed., John Wiley, New York, pp. 535-597 (1983).
Hanazato et al.,IEEE Transactions Electron. Devices; ED33:47;51 (1986).
Hoopman, “Microchanneled Structures,” Applied Technology Laboratory, 3M Center, St. Paul, MN 55144-1000.
Howe et al.,IEEE Transactions Electron Devices, ED33:499-506 (1986).
Hung et al,Med. & Biol. Engng,, 9:237-245 (1971).
Jonsson,Methods in Enzymology, 137:381-389 (1988).
Kennedy et al.,Clin. Chem. Acta., 70:1-31 (1976).
Kenny et al.,Appl. Phys. Lett., 58:100-102 (1991).
Kikuchi et al., “Microchannels Made on Silicon Wafer for Measurement of Flow Properties of Blood Cells,”Biorheology, 26:1055 (1989), Abstract.
Kittilsland et al.,Journal de Physique, 49 (C4):641-644 (1988).
Kittilsland et al.,Sensors and Activators, A21-A23:904-907 (1990).
Kricka et al., “Liquid Transport in Micron and Submicron Channels,”SPIE, 1167:159-168 (1989).
Kricka et al.,Clin Chem., 26:741-744 (1980).
LaCelle,Blood Cells, 12:179-189 (1986).
Mandenius et al.,Anal. Biochem., 137:106-114 (1984).
Mandenius et al.,Anal. Biochem., 170:68-72 (1988).
Mandenius et al.,Methods in Enzymology, 137:388-394 (1988).
Manz et al.,Trends in Anal. Chem., 10:144-149 (1991).
Masuda et al.,Proc. IEEE/IAS Meeting, pp. 1549-1553 (1987).
McCartney et al.,Cancer Res., 41:3046-3051 (1981).
Moghissi et al.,Am. J. Obstet. Gynecol., 114:405-(1972).
Nakamura,Immunochemical Assays and Biosensor Technology for the 1990's, American Society of Microbiology, Washington, D.C., pp. 205-215 (1992).
Nakamura et al.,Anal. Chem., 63:268-272 (1991).
Parce et al.,Science, 24:243-247 (1989).
Rosenberg et al.,Clin. Chem., 30:1462-1466 (1984).
Rosenberg et al.,Clin. Chem., 31:1444-1448 (1985).
Sankolli et al.,J. Imun. Methods, 104:191-194 (1987).
Sato, et al.,Sensors and Actuators, A21-A23: 948-951 (1990).
Shoji, et al.,Sensors and Actuators, 15:101-107 (1988).
Stange et al.,Biomaterials, 9:3-6 (1988).
Van Lintel,Sensors and Actuators, 15:153-167 (1988).
Wallis et al.,J. Amer. Ceramic Soc., 53:563-567 (1970).
Washizu et al.,Proceedings IEEE/IAS Meeting, pp. 1735-1740 (1988).
Weissman et al.Am Inst. Chem. Eng. J. 17:25-30 (1971).
Zemel et al. in:Fundamentals and Applications of Chemical Sensors, D. Schuetzle and R. Hammerle, Eds., Washington, D.C., 1986, p. 2-38.
Biotrack, Ciba Corning, May, 1989.
Wilding,Advanced Hospital Technology Laboratory, Oct. 1990 pp. 38-42.
Roche, On-Trak™, Sep., 1988.
Angell et al.,Scientific American, 248:44-55 (1983).
Appenzeller,Science, 254:1300-1342 (1991).
Brown, “Development of a Stopped-Flow Cytometer,” NSF Grant No. ISI 87-60730, Abstract.
Brunette,Exper. Cell Res., 167:203-217 (1986).
Brunette,Exper. Cell. Res., 164:11-26 (1986).
Kinosita et al., “Dual-View Microscopy With A Single Camera: Real-Time Imaging Of Molecular Orientations And Calcium,”J. Cell Biol, 115:67-73 (1991) (Abstract).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Device and method for the detection of an analyte utilizing... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Device and method for the detection of an analyte utilizing..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Device and method for the detection of an analyte utilizing... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3629234

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.