Surgery – Instruments – Cyrogenic application
Reexamination Certificate
2001-06-01
2004-06-29
Peffley, Michael (Department: 3739)
Surgery
Instruments
Cyrogenic application
C607S122000, C606S041000
Reexamination Certificate
active
06755822
ABSTRACT:
FIELD OF THE INVENTION
The present invention relates generally to devices and methods for the treatment of cardiac arrhythmia and more specifically relates to devices and methods for the treatment of focal atrial arrhythmia.
BACKGROUND INFORMATION
Cardiac rhythm is maintained by precisely timed nerve signals electrically exciting and being conducted through cardiac tissue to stimulate synchronous contractions of the four heart chambers (2 ventricles and 2 atria). In a normal sinus rhythm, the nerve signals are typically conducted along paths initiating at the sino-atrial (SA) node and passing from there through the atrioventricular (AV) node and the bundle of His to the ventricular myocardial tissue.
Potentially dangerous abnormal cardiac rhythms, or arrhythmias, including atrial fibrillation, are common medical conditions which may result from disturbances in the site of origin and/or the pathways of conduction of the nerve signals exciting contraction of the four chambers of the heart. The site of origin and pathways of conduction of these signals are currently mapped, for example using an electrocardiograph (ECG) in conjunction with mapping methods such as those described in U.S. Pat. No. 4,641,649 to Walinsky et al.
One common type of atrial fibrillation occurs when the contraction initiating signals originate within one or more of the pulmonary veins rather than at the SA node. These atrial arrhythmias have been treated by a variety of methods including pharmocologic treatments, highly invasive surgical procedures and linear and circumferential RF ablations of the myocardial wall. However, each of these methods has drawbacks, e.g., the pain and extended recovery time for invasive surgery, relative ineffectiveness of pharmacologic treatments and restenosis at the ablation site due to the application of RF energy or other heat based therapies thereto.
SUMMARY OF THE INVENTION
The present invention is directed to a method and apparatus for ablating tissue within a patient comprising inserting into a patient's venous system a substantially rigid sheath, piercing a desired point of penetration in the patient's interatrial septum to pass the rigid sheath through the interatrial septum into the patient's left atrium, maneuvering a flexible section mounted on the rigid sheath into a position in which a distal end of the flexible section is located adjacent to a portion of tissue to be ablated, the flexible section including an occluding structure which has a retracted position and extended position, and passing an ablation catheter through the flexible section so that an ablation tip of the ablation catheter is adjacent to the portion of tissue to be ablated.
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W. Haverkame et al., “Non-pharmacological treatment of arrhythmla using the method of trans-catheter ablation”, Grud Serdechnososudistaia Khir, Aug. 1991, pp. 6-16, vol. 8, [ABSTRACT].
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Ayers Gregory M.
Castellano Thomas M.
Reu Eugene Brian
CryoCor, Inc.
Fay Kaplun & Marcin LLP
Peffley Michael
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