Device and method for self contained solid phase immunodiffusion

Details Device and method for self contained solid phase immunodiffusion Device and method for self contained solid phase immunodiffusion

1991-12-27

1992-12-08

Warden, Robert J.

Chemistry: analytical and immunological testing

Biospecific ligand binding assay

422 56, 422 57, 422 61, 436524, 436528, 436531, G01N 33545

Patent

active

051697890

ABSTRACT:
A device and method for a self contained solid phase immunodiffusion assay. The device is comprised of a sample collector, and a pre-fabricated laminate which can be used in many different forms. For example, the same collector and laminate can be used with a tube having compartmentalized reagents. The seals can be broken through pressure on the sample collector. The sample collector is pushed through the seals, mixed with reagent, and then pushed into a ligand receptor reaction area which is part of the laminate. The tip of the sample collector contacts diffusable or porous membranes or filters and transfers the reactants to a capture membrane wherein a ligand receptor reaction can be examined by the naked eye or otherwise.

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