Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is inorganic
Reexamination Certificate
2007-01-30
2007-01-30
Le, Long V. (Department: 1641)
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
Carrier is inorganic
C436S518000, C436S524000, C702S027000, C422S051000, C422S068100, C422S082010
Reexamination Certificate
active
11036367
ABSTRACT:
A device for quantitatively determining an analyte is provided to conspicuously improve the performance of the quantitative determination. This device is equipped with a flow channel, an analyte detecting unit for capturing and detecting the analyte, and a quantitative measurement unit for quantitatively determining the analyte, wherein a signal generated when the analyte detecting unit has detected the analyte is divided into a plurality of parts in the direction of the flow in the flow channel at the quantitative measurement unit for processing. Also provided are technologies including one for controlling the density of molecules attached to the surface of a solid. In these technologies, when molecules are attached to a substrate, the density of attached molecules is controlled, by having an electrolyte also present in a solution containing the molecules to adjust the screening effect by the electrolyte, and by taking into consideration the effective size of a molecule.
REFERENCES:
patent: 4803688 (1989-02-01), Lawandy
patent: 5064655 (1991-11-01), Uster et al.
patent: 5106468 (1992-04-01), Chimenti
patent: 5653939 (1997-08-01), Hollis et al.
patent: 5952095 (1999-09-01), Beall et al.
patent: 6616987 (2003-09-01), Morfill et al.
patent: 6915214 (2005-07-01), Dukhin et al.
patent: 2002/0015792 (2002-02-01), Nagayama et al.
patent: 2002/0070166 (2002-06-01), Backhouse
patent: 2002/0126261 (2002-09-01), Nomura et al.
patent: 2001-235468 (2001-08-01), None
patent: WO 9418834 (1994-09-01), None
Suzuki et al., “Quantitative analysis of DNA orientation in stationary AC electric fields using fluorescence anistropy”, 1998, IEEE Transactions on Industry Applications, vol. 34, pp. 75-83.
Carbeck et al., “Measuring the size and charge of proteins using protein charge ladders, capillary electrophoresis, and electrokinetic models of colloids”, 2001, J. Am. Chem. Soc., vol. 123, pp. 1252-1253.
Hagerman et al., “Electrostatic contribution to the stiffness of DNA molecules of finite length”, 1983, Biopolymers, vol. 22, pp. 811-814.
A. Ulman; “Formation and Structure of Self-Assembled Monolayers;”Chem. Rev.; vol. 96; 1996; pp. 1533-1554.
S.O. Kelley, et al.; “Electrochemistry of Methylene Blue Bound to a DNA-Modified Electrode;”Bioconjugate Chem.; vol. 8; 1997; pp. 31-37.
A.W. Peterson, et al.; “The effect of surface probe density on DNA hybridization;”Nucleic Acids Research; vol. 29; No. 24; pp. 5163-5168.
T.M. Herne, et al.; “Characterization of DNA Probes Immobilized on Gold Surfaces;”J. Am. Chem. Soc.; vol. 119; 1997; pp. 8916-8920.
A.B. Steel, et al; “Electrochemical Quantitation of DNA Immobilized on Gold;”Anal. Chem.; vol. 70; 1998; pp. 4670-4677.
M.J. Heller; “DNA Microarray Technology: Devices, Systems and Applications;”Annu. Rev. Biomed. Eng.; vol. 4; 2002; pp. 129-153 and Fig. 1 (1 Sheet.).
Arinaga Kenji
Rant Ulrich
Armstrong Kratz Quintos Hanson & Brooks, LLP
Fujitsu Limited
Jung Unsu
Le Long V.
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