Device and method for particle complex handling

Liquid purification or separation – Processes – Using magnetic force

Reexamination Certificate

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Details

C210S222000, C210S223000, C436S164000, C436S526000, C436S805000, C436S806000, C435S287200, C435S287300, C435S288400, C435S288500, C422S400000, C422S082050, C073S053010

Reexamination Certificate

active

07993525

ABSTRACT:
An embodiment of the invention relates to a device for detecting an analyte in a sample. The device comprises a fluidic network and an integrated circuitry component. The fluidic network comprises a sample zone, a cleaning zone and a detection zone. The fluidic network contains a magnetic particle and/or a signal particle. A sample containing an analyte is introduced, and the analyte interacts with the magnetic particle and/or the signal particle through affinity agents. A microcoil array a mechanically movable permanent magnet is functionally coupled to the fluidic network, which are activatable to generate a magnetic field within a portion of the fluidic network, and move the magnetic particle from the sample zone to the detection zone. A detection element is present which detects optical or electrical signals from the signal particle, thus indicating the presence of the analyte.

REFERENCES:
patent: 6632655 (2003-10-01), Mehta et al.
patent: 2003/0012693 (2003-01-01), Otillar et al.
patent: 2005/0284817 (2005-12-01), Fernandez et al.
patent: 2008/0160630 (2008-07-01), Liu et al.
patent: 2008/0160634 (2008-07-01), Su et al.

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