Liquid purification or separation – Processes – Using magnetic force
Reexamination Certificate
2011-08-09
2011-08-09
Reifsnyder, David A (Department: 1776)
Liquid purification or separation
Processes
Using magnetic force
C210S222000, C210S223000, C436S164000, C436S526000, C436S805000, C436S806000, C435S287200, C435S287300, C435S288400, C435S288500, C422S400000, C422S082050, C073S053010
Reexamination Certificate
active
07993525
ABSTRACT:
An embodiment of the invention relates to a device for detecting an analyte in a sample. The device comprises a fluidic network and an integrated circuitry component. The fluidic network comprises a sample zone, a cleaning zone and a detection zone. The fluidic network contains a magnetic particle and/or a signal particle. A sample containing an analyte is introduced, and the analyte interacts with the magnetic particle and/or the signal particle through affinity agents. A microcoil array a mechanically movable permanent magnet is functionally coupled to the fluidic network, which are activatable to generate a magnetic field within a portion of the fluidic network, and move the magnetic particle from the sample zone to the detection zone. A detection element is present which detects optical or electrical signals from the signal particle, thus indicating the presence of the analyte.
REFERENCES:
patent: 6632655 (2003-10-01), Mehta et al.
patent: 2003/0012693 (2003-01-01), Otillar et al.
patent: 2005/0284817 (2005-12-01), Fernandez et al.
patent: 2008/0160630 (2008-07-01), Liu et al.
patent: 2008/0160634 (2008-07-01), Su et al.
Liu David J.
Su Xing
Swartz Kenneth B.
Wu Kai
Yamakawa Mineo
Intel Corporation
Pillsbury Winthrop Shaw & Pittman LLP
Reifsnyder David A
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