Device and method for monitoring leukocyte migration

Details Device and method for monitoring leukocyte migration Device and method for monitoring leukocyte migration

2003-10-21

2008-09-02

Corcoran, Gladys (Department: 1797)

Chemistry: molecular biology and microbiology

Apparatus

Including measuring or testing

C435S288400, C435S288300, C435S287800, C435S305300, C435S305100, C435S278000

Reexamination Certificate

active

07419823

ABSTRACT:
A device for monitoring leukocyte migration is provided. The invention also provides a method of using the device to monitor leukocyte migration in the presence of physiological shear flow and therefore simulate physiological conditions of a blood vessel in vivo. The invention further provides a method of using the device to high-throughput screen a plurality of test agents. The present invention further provides a flexible assay system and numerous assays that can be used to test biological interactions and systems. Laminar flow gradients are employed that mimic gradient situations present in vivo.

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