Device and method for grinding biological samples

Solid material comminution or disintegration – Processes – With cell rupturing or liberation of contained liquids

Reexamination Certificate

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C241S021000, C241S169100, C241S199120

Reexamination Certificate

active

07370819

ABSTRACT:
In a biological sample grinding device and method, a bearing having a plurality of rolling elements disposed between a pair of rings is disposed in a container in which a fluid having at least one biological sample particle therein is introduced. With the bearing immersed in the fluid having the biological sample particle therein, one ring of the bearing is rotated relative to the other ring thereof, whereupon the rolling elements roll between the pair of rings and, in response thereto, the biological sample particle is drawn by the fluid between the pair of rings where it is subject to being crushed or ground between at least one of the rolling elements and at least one of the rings. A baffle can be disposed in the container for inhibiting the rotation of the fluid and, hence, the introduction of air into the fluid.

REFERENCES:
patent: 4307846 (1981-12-01), Spelsberg
patent: 5390859 (1995-02-01), Rajasekaran
patent: 5829696 (1998-11-01), DeStefano et al.
Joseph Edward Shigley: “Mechanical Engineering Design”; Second Edition; McGraw-Hill Book Company; copyright 1963, 1972; (6 pp.).

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