Chemistry: electrical and wave energy – Processes and products – Electrophoresis or electro-osmosis processes and electrolyte...
Patent
1998-04-22
2000-02-22
Warden, Jill
Chemistry: electrical and wave energy
Processes and products
Electrophoresis or electro-osmosis processes and electrolyte...
204600, G01N 2726, G01N 27447
Patent
active
060276231
ABSTRACT:
A device for fractionating macromolecules in a fluid medium includes a plurality of individual obstacles which are arranged on a substrate in rows and columns. An electric field is provided and oriented to move the macromolecules in migration through fluid channels that are established between the columns of obstacles. Each obstacle has mutually symmetrical right and left front walls which are inclined to a respective fluid channel. Consequently, as macromolecules diffuse through the fluid medium from a fluid channel during their migration through the device, the front walls of the obstacles redirect them back into the same fluid channel from which they diffused. As a result, the faster diffusing, smaller macromolecules take longer to migrate through the fluid channels of the device. Eventually, because the diffusion rate of the macromolecules depends on their size, the positions of the macromolecules in the device reflect their respective diffusion rates, and therefore their size.
REFERENCES:
patent: 4683202 (1987-07-01), Mullis
patent: 4811218 (1989-03-01), Hunkapiller et al.
patent: 4965188 (1990-10-01), Mullis et al.
patent: 5038852 (1991-08-01), Johnson et al.
patent: 5121320 (1992-06-01), Aoki et al.
patent: 5427663 (1995-06-01), Austin et al.
patent: 5637458 (1997-06-01), Frankel et al.
patent: 5837115 (1998-11-01), Austin et al.
Starsiak Jr. John S.
Toyo Technologies Inc.
Warden Jill
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