Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Electrical therapeutic systems
Patent
1999-02-25
2000-06-20
Schaetzle, Kennedy J.
Surgery: light, thermal, and electrical application
Light, thermal, and electrical application
Electrical therapeutic systems
600513, 6048911, A61M 5142
Patent
active
060788348
ABSTRACT:
The invention disclosed herein relates to an implantable medical device for detection and treatment of syncope comprising an algorithm for determining the presence of syncope based on physiological activity associated with the onset of a syncopal episode, and a means for infusion a drug. Drug infusion therapy may be used along or in combination with pacing. The physiological activities detected and used by the device are selected from the group including changes in heart rate, heart rate variability, QT interval, PR interval, pressure, blood flow, vagal nerve activity, temperature, pH, and AV conduction times, respiration rate, position, motion, and combinations thereof. Drugs which may be used with the invention include pharmaceutical compositions which are capable of both endocardial administration and treatment of syncope, such as compositions comprising beta-blockers.
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Benditt David
Buscemi Paul J.
Lurie Keith G.
Obino Stanislao F.
PharmaTarget, Inc.
Schaetzle Kennedy J.
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