Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Electrical therapeutic systems
Patent
1997-04-10
1999-07-06
Kamm, William E.
Surgery: light, thermal, and electrical application
Light, thermal, and electrical application
Electrical therapeutic systems
607 25, 600516, 604 19, A61M 5142
Patent
active
059192100
ABSTRACT:
The invention disclosed herein relates to an implantable medical device for detection and treatment of syncope comprising an algorithm for determining the presence of syncope based on physiological activity associated with the onset of a syncopal episode, and a means for infusion a drug. Drug infusion therapy may be used along or in combination with pacing. The physiological activities detected and used by the device are selected from the group including changes in heart rate, heart rate variability, QT interval, PR interval, pressure, blood flow, vagal nerve activity, temperature, pH, and AV conduction times, respiration rate, position, motion, and combinations thereof. Drugs which may be used with the invention include pharmaceutical compositions which are capable of both endocardial administration and treatment of syncope, such as compositions comprising beta-blockers.
REFERENCES:
patent: 3358690 (1967-12-01), Cohen
patent: 3593718 (1971-07-01), Krasner et al.
patent: 3857399 (1974-12-01), Zacouto
patent: 4009721 (1977-03-01), Alcidi
patent: 4146029 (1979-03-01), Ellinwood, Jr.
patent: 4193393 (1980-03-01), Schlager
patent: 4202339 (1980-05-01), Wirtzfeld et al.
patent: 4228803 (1980-10-01), Rickards
patent: 4252124 (1981-02-01), Maurer et al.
patent: 4312355 (1982-01-01), Funke
patent: 4313442 (1982-02-01), Knudson et al.
patent: 4428378 (1984-01-01), Anderson et al.
patent: 4566456 (1986-01-01), Koning et al.
patent: 4730619 (1988-03-01), Koning et al.
patent: 4791931 (1988-12-01), Slate
patent: 4960129 (1990-10-01), dePaola et al.
patent: 5040533 (1991-08-01), Fearnot
patent: 5065759 (1991-11-01), Begemann et al.
patent: 5113859 (1992-05-01), Funke
patent: 5213098 (1993-05-01), Bennett et al.
patent: 5233984 (1993-08-01), Thompson
patent: 5330505 (1994-07-01), Cohen
patent: 5342404 (1994-08-01), Alt et al.
patent: 5441525 (1995-08-01), Shelton et al.
patent: 5464434 (1995-11-01), Alt
patent: 5501701 (1996-03-01), Markowitz et al.
patent: 5514163 (1996-05-01), Markowitz et al.
patent: 5527344 (1996-06-01), Arzbaecher et al.
patent: 5540728 (1996-07-01), Shelton et al.
patent: 5560368 (1996-10-01), Berger
patent: 5676686 (1997-10-01), Jensen et al.
K. Lurie et al., "Syncope and the Autonomic Nervous System", Journal of Cardiovascular Electrophysiology, vol. 7, No. 8, Aug. 1996, pp. 760-776.
W. Kapoor et al., "Upright Tilt Testing in Evaluating Syncope: A Comprehensive Literature Review", The American Journal of Medicine, vol. 97, Jul. 1994, pp. 78-88.
R. Sutton et al., "The Clinical Spectrum of Neurocardiogenic Syncope", Journal of Cardiovascular Electrophysiology, vol. 6, No. 7, Jul. 1995, pp. 569-576.
P. Chang-Sing et al., "Syncope: Evaluation and Management/A Review of Current Approaches to This Mulifaceted and Complex Clinical Problem", Cardiology Clinics, vol. 9, No. 4, Nov. 1991, pp. 641-651.
M. Gammage et al., "Initial Experience with a Rate Drop Algorithm in Malignant Vasovagal Syndrome", European Journal of Cardiac Pacing and Electrophysiology, vol. 5, No. 1, 1995, 5 pages.
S. Jasbir et al., Cardiac Pacing During Neurocardiogenic (Vasovagal) Syncope, Journal of Cardiovascular Electrophysiology, vol. 6, No. 9, Sep. 1995, pp. 751-760.
T. Kus et al., "Vasovagal Syncope: Management with Atrioventricular Sequential Pacing and Beta-Blockade", The Canadian Journal of Cardiology, vol. 5, No. 8, Nov./Dec. 1989, 5 pages.
D. Benditt et al., "Cardiac Pacing for Prevention of Recurrent Vasovagal Syncope", Annals of Internal Medicine, vol. 122, No. 3, Feb. 1995, pp. 204-209.
Benditt David
Buscemi Paul J.
Lurie Keith G.
Obino Stanislao F.
Kamm William E.
PharmaTarget, Inc.
Schaetzle Kennedy J.
LandOfFree
Device and method for detection and treatment of syncope does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Device and method for detection and treatment of syncope, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Device and method for detection and treatment of syncope will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-895848