Device and method for detecting myoglobin

Chemistry: physical processes – Physical processes – Crystallization

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422 56, G01N 3316, G01N 3122

Patent

active

041893042

ABSTRACT:
A test device and method for detecting myoglobin in the presence of hemoglobin in a fluid test sample. The test device comprises a chromatographic medium incorporating serum, haptoglobin and/or antiserum which binds or retards hemoglobin while permitting myoglobin to traverse the length of the test device. A test sample of body fluid is placed in contact with an appropriate portion of the chromatographic medium of said test device; hemoglobin in the body fluid is retained or retarded by the serum, haptoglobin and/or antiserum; and myoglobin in the sample traverses the length of the medium and contacts reagent means at a predetermined location thereon, resulting in a detectable response thereat.

REFERENCES:
patent: 3290117 (1966-12-01), Adams, Jr.
patent: 3699003 (1972-10-01), Kronish
patent: 3723064 (1973-03-01), Liotta
patent: 3868219 (1975-02-01), Hurenkamp
patent: 3875014 (1975-04-01), Forgione
patent: 3915639 (1975-10-01), Friedenberg
patent: 3975161 (1976-08-01), Svoboda
patent: 4017261 (1977-04-01), Svoboda
patent: 4071317 (1978-01-01), Lam
patent: 4071321 (1978-01-01), Lam
patent: 4094647 (1978-06-01), Deutsch
Chemical Abstracts, 62: 940b, (1965).

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