Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism
Patent
1995-07-24
1997-02-04
Beisner, William
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving viable micro-organism
4352871, 4352879, 4352972, 73 38, 73 6447, 324450, 324 711, 422101, C12Q 102, C12M 306, C12M 112
Patent
active
055996884
ABSTRACT:
The invention provides a compact device and simple method for circulating fluid over the surface of a membrane. The device comprises a housing that in combination with the surface of the membrane defines an enclosed volume through which the fluid is circulated. Some embodiments will include a membrane holding layer, a fluid dispersing layer, or both. The membrane holding layer has an opening through it to expose a predetermined surface area of the membrane to the fluid. The dispersing layer has a set of openings, typically slits, through the dispersing layer to disperse fluid over the surface of the membrane. Some embodiments may include electrodes for sensing or applying electrical potential to the membrane. A particularly preferred embodiment comprises a double sided device including a first housing, dispersing layer and membrane holding layer on one side of a membrane and a second housing dispersing layer and membrane holding layer on the other side of the membrane. A separate fluid may be circulated through each housing over the two sides of the membrane. In some embodiments the membrane will be provided with at least one ridge that defines at least two parallel channels in which different types of cells may be held.
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Beisner William
Precision Instrument Design
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