Image analysis – Applications – Biomedical applications
Reexamination Certificate
2002-03-18
2008-11-04
Johns, Andrew W. (Department: 2624)
Image analysis
Applications
Biomedical applications
C424S009200, C382S133000, C435S286100, C435S808000, C435S288700, C435S029000, C435S030000, C356S036000, C356S038000, C356S338000, C356S341000, C356S343000
Reexamination Certificate
active
07447340
ABSTRACT:
The invention relates to a device (10) and a method for automatically eliciting a thermal avoidance response in nematodes, particularly in order to test pharmaceutical substances. The device (10) has a bearing surface (12) on which sample containers (14) of nematodes (16) are disposed, a laser (18), a selective laser-beam interrupter (27) to regulate the length of the laser pulse, aft and a scanner (22) for projecting and focussing the laser beam and for controlling a deflection. A light source (28) illuminates the sample container (14) with light, which brings about a contrast in the nematodes in the container. An additional light source (29) can also illuminate the sample container (14) with light in order to excite fluorescence-labeled areas of the nematodes, causing them to fluoresce. A real-time image processing device connected to the camera (30) determines the respective positions of all areas relevant for laser irradiation of the nematodes and makes this information available to a controller (32). The beam path of laser (18) is directed sequentially to different areas of individual nematodes by the controller using the scanner (22).
REFERENCES:
patent: 5480804 (1996-01-01), Niwa et al.
patent: 6444665 (2002-09-01), Helton et al.
patent: 6702996 (2004-03-01), Baumeister et al.
patent: 6995841 (2006-02-01), Scott et al.
patent: 2005/0062837 (2005-03-01), Kim
patent: 2007/0111027 (2007-05-01), Chen et al.
patent: 0935132 (1999-02-01), None
patent: 199 24 929 (2000-12-01), None
patent: 0 935 132 (1999-08-01), None
patent: 2231958 (1990-11-01), None
patent: 2231958 (1990-11-01), None
patent: 0284660 (1997-08-01), None
Distribution and movement ofCaenorhabditis eleganson a thermal gradient, Yamada et al, May 2003.
Thermal avoidance inCaenorhabditis elegan: An approach to the study of npciception, Aug. 1999.
Braungart Evelyn
Tovar Karlheinz
Weidner Gerhard
Bitar Nancy
Hanley, Esq Elizabeth A.
Johns Andrew W.
Lahive & Cockfield LLP
NemaGain Research, LLC
LandOfFree
Device and method for automatically producing a thermal... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Device and method for automatically producing a thermal..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Device and method for automatically producing a thermal... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4022197