Surgery – Diagnostic testing – Respiratory
Reexamination Certificate
2008-03-25
2008-03-25
Nasser, Robert (Department: 3735)
Surgery
Diagnostic testing
Respiratory
C073S023300, C422S084000
Reexamination Certificate
active
10474979
ABSTRACT:
Device and method for non-invasively monitoring asthma and other respiratory diseases, as well as non-respiratory diseases. The method includes collecting condensate from a subject's breath, testing the condensate to determine its acetic acid/acetate level or concentration, and evaluating these properties to determine the presence, absence or status of a respiratory or non-respiratory disease in the subject. The method may also include, prior to the testing step, standardizing the volatile substances that may be present within the condensate in a degassing or gas standardizing step. The device includes a mouthpiece apparatus configured to receive breath from a subject, a condensation apparatus to condense the subject's breath and produce a condensate, and a collection apparatus having a collection chamber containing means for testing the condensate to determine the acetic acid and/or acetate concentration. The device may also include a system for removing or standardizing the volatile substances that may be present with the condensate. The device and method may be utilized without condensing a subject's breath and collecting the same.
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Gaston Benjamin M.
Hunt John F.
Macdonald Timothy L.
Vaughan John W.
Decker Robert J.
Nasser Robert
University of Virginia Patent Foundation
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