Development of method for screening physiologically active...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C424S009100, C424S174100, C514S04400A

Reexamination Certificate

active

07378237

ABSTRACT:
A method for screening the effect of a segment A (chemical species A) on a substance (for example, a cell) containing DNA or RNA by using artificial chemical species. Namely, a method of detecting or identifying the function of a chemical species A on a substance containing DNA or RNA by using one or more chemical species represented by the following general formula (I) which are capable of recognizing a DNA base sequence; a kit therefor; and a plate to be used therein: B-L-A (I) wherein B represents a chemical structure containing an non-natural base capable of recognizing a DNA base sequence; A represents a chemical structure having an interaction with DNA; and L represents a linker whereby the chemical structures A and B can be linked together.

REFERENCES:
patent: 5273991 (1993-12-01), Lee
patent: 6713633 (2004-03-01), Sugiyama et al.
patent: WO-00/58312 (2000-10-01), None
patent: WO 00/58312 (2000-10-01), None
The Chemical Society of Japan (CSJ) ed.,Lecture Proceedings II of the 74thSpring Annual Meeting, the Chemical Society of Japan(SCJ), (Mar. 14, 1998).

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