Developer for fecal occult blood tests

Chemistry: analytical and immunological testing – Hemoglobin – myoglobin – or occult blood

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25218625, 25218626, 25218638, 25218642, 2524081, 435 28, 436904, G01N 2178, G01N 3372

Patent

active

049719149

ABSTRACT:
Fecal occult blood tests of enhanced sensitivity, specificity, and readability are provided by employing (1) a developer or complete reagent solution that uses as a solvent system a solvent comprising at least about 50% by volume of a solvent for iron protoporphyrins such as dimethyl sulfoxide and/or (2) a multi-chromagen comprised of a mixture of guaiac and ABTS. Test results may be further improved by incorporating hemoprotein solubilizing agents, plant peroxidase inhibitors, iron/copper chelating agents, accelerators and buffers in the developer/reagent.

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