Deuteroporphyrin derivative or salt thereof

Details Deuteroporphyrin derivative or salt thereof Deuteroporphyrin derivative or salt thereof

1985-01-11

1987-01-06

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424 9, C07D48722

Patent

active

046345574

ABSTRACT:
Disclosed herein is a deuteroporphyrin derivative represented by the following general formula: ##STR1## wherein one of R.sub.1 and R.sub.2 means --CH(CH.sub.3)--OR, R being a lower alkyl group, and the other denotes --CH.dbd.CH.sub.2, or R.sub.1 and R.sub.2 both mean --CH(CH.sub.3)--OR, R having the same meaning as defined above, or a salt thereof. The deuteroporphyrin derivative or its salt can be readily obtained in its pure form and is useful as a photosensitizer in the laser irradiation therapy of cancers.

REFERENCES:
patent: 3004985 (1961-10-01), Obika et al.
Dolphin, The Porphyrins, vol. 1, Academic Press, New York (1978), pp. 297-298.
Kessel et al., Porphyrin Photosensitization, Plenum Press, New York (1983), pp. 165-179.
Chemical Abstracts, vol. 97, No. 21, Nov. 22nd, 1982, p. 408, No. 177901y, "Some Patterns in the Transport . . . ".
Chemical Abstracts, vol. 93, No. 3, Jul. 21st, 1980, p. 59, No. 19225u, "Toxic and Radioprotective Properties of . . . ".

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