Deuterium-enriched oseltamivir

Details Deuterium-enriched oseltamivir Deuterium-enriched oseltamivir

2011-03-29

2011-03-29

Zucker, Paul A (Department: 1621)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

C560S125000

Reexamination Certificate

active

07915309

ABSTRACT:
The present application describes deuterium-enriched oseltamivir, pharmaceutically acceptable salt forms thereof, and methods of treating using the same.

REFERENCES:
patent: 5763483 (1998-06-01), Bischofberger et al.
patent: 6221335 (2001-04-01), Foster
patent: 6440710 (2002-08-01), Keinan et al.
patent: 6603008 (2003-08-01), Ando et al.
patent: 7517990 (2009-04-01), Ito et al.
patent: 2007/0082929 (2007-04-01), Gant et al.
patent: 2007/0197695 (2007-08-01), Potyen et al.
patent: 95/26325 (1995-10-01), None
Oliyai et al, Pharmaceutical Research, Biexponential Decomposition of a Neuraminidase Inhibitor Prodrug (GS-4104) in Aqueous Solution, 1998, 15(8), pp. 1300-1304.
Dyck, Journal of Neurochemistry vol. 46 Issue 2, pp. 399-404 (1986).
Tonn, Biological Mass Spectrometry vol. 22 Issue 11, pp. 633-642 (1993).
Haskins, Biomedical Spectrometry vol. 9 Issue 7, pp. 269-277 (1982).
Wolen, Journal of Clinical Pharmacology 1986; 26: 419-424.
Browne, Journal of Clinical Pharmacology1998; 38: 213-220.
Baillie, Pharmacology Rev.1981; 33: 81-132.
Gouyette, Biomedical and Environmental Mass Spectrometry, vol. 15, 243-247 (1988).
Cherrah, Biomedical and Environmental Mass Spectrometry vol. 14 Issue 11, pp. 653-657 (1987).
Pieniaszek, J Clin Pharmacol.1999; 39: 817-825.
Honma et al., Drug Metab Dispos 15 (4): 551 (1987).
Siegel, Marshall M.; Applied Spectroscopy (1989), 43(7), 1215-22.
Plachy et al, Journal of Labelled Compounds and Radiopharmaceuticals, Synthesis of Di-t-alkyl Nitroxides Enriched in 2H and 12C, 1990, 28(1), pp. 99-110.
Aldrich, Aldrich Handbook of Fine Chemicals and Laboratory Equipment, 2002, p. 21.
Kushner, D.J.; Pharmacological Uses and Perspectives of Heavy Water and Deuterated Compounds; Canadian Journal of Physiology and Pharmacology 1999, 77(2), 79-88.
Oliyai et al.: Pharmaceutical Research, Biexponential Decomposition of Neuraminidase Inhibitor Prodrug (GS-4104) In Aqueous Solution; 1998 15(8) pp. 1300-1304.
Sweeny, D.J., et al., Metabolism of the Influenza Neuraminidase Inhibitor Prodrug Oseltamivir in the Rat, Drug Metabolism and Disposition 2000, 28)7), 737-41.
PCT/US09/67425 International Search Report and Written Opinion (corresponding PCT application) mailed Sep. 29, 2008.

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