Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ether doai
Patent
1995-02-15
1998-08-04
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ether doai
A61V 3108
Patent
active
057894507
ABSTRACT:
Use of D2-sevoflurane is disclosed as an inhalational anesthetic. Deuterated sevoflurane possess all of the desirable qualities of sevoflurane as an anesthetic and is metabolized more slowly thereby reducing potentially toxic inorganic fluoride release. More particularly, the compound fluorodideutero methyl 1,1,1,3,3,3-hexafluoropropyl ether is disclosed as well as a method for synthesis.
REFERENCES:
Holaday et al., Deuteration Reduced Significantly the Biotransformation of Sevoflurane, Am Soc. of Anesthesiologist, Inc. 57:3 Sep. 1982.
Baker Max T.
Tinker John H.
Goldberg Jerome D.
Lind Charles F.
University of Iowa Research Foundation
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