Detoxifying-medicinal emulsions

Details Detoxifying-medicinal emulsions Detoxifying-medicinal emulsions

1978-02-13

1980-01-15

Rosen, Sam

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

424127, 424154, 424358, 424365, A61K 3748, A61K 4700, A61K 3308

Patent

active

041839188

ABSTRACT:
This invention relates to the use of liquid membrane technology in preparing medicinals. The medicinals prepared by this invention may be ingested and may be utilized as traps for toxins present in the GI (gastrointestinal) tract, or as slow-release compositions of drugs, or as reactors. In the trap embodiment, the liquid membrane encapsulated medicinal is an emulsion comprising an exterior phase which is immiscible with the liquids present in the GI tract and permeable to the toxins therein, and an interior phase which is immiscible with the exterior phase and comprises a reagent capable of converting said toxin into a nonpermeable form. In addition, hydrophilic adsorbents, such as a hydrophilic carbon or a silica gel, may be encapsulated in the emulsions of the instant invention. When the compositions of the instant invention are utilized as slow-release drugs, the interior phase of the emulsion will comprise a drug which is slightly soluble in the exterior phase of the emulsion whereby said drug permeates through said exterior phase of the emulsion over a period of time into the GI tract. The third method for utilizing the compositions of the instant invention comprises encapsulating a catalyst for a reaction which is desired to be carried out in the GI tract. In this embodiment the reactants present in the GI tract permeate through the exterior phase of the emulsion into an interior phase wherein said catalyst, for example, an enzyme, converts the permeated reactants to reaction products. The reaction products then may permeate through the exterior phase back into the GI tract. In all cases, the liquid membrane encapsulated medicinals may be administered by either oral ingestion or injection anywhere else into the GI tract.

REFERENCES:
patent: 4115313 (1978-09-01), Lyon et al.

Affiliated with

Also associated with

Rating

Detoxifying-medicinal emulsions does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Detoxifying-medicinal emulsions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Detoxifying-medicinal emulsions will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1028357