Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...
Patent
1978-12-08
1980-12-23
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated via claimed linking group, bond, chelating agent,...
536115, 536119, A61K 3170
Patent
active
042410541
ABSTRACT:
Non-absorbable polyol polyesters dissolve toxic lipophilic compounds in the stomach and intestine of humans and lower animals and thus decrease their absorption. The polyol polyesters also dissolve the toxic, lipophilic materials and their metabolites if they are excreted in bile, and prevent their resorption. The invention thus provides a means for detoxifying humans and lower animals which have ingested toxic lipophilic materials (e.g., DDT, Kepone, PCB, PBB) by accelerating the excretion of such materials that have accumulated in the body. The process involves oral administration to a human or lower animal in need of such treatment of a sufficient amount of a non-absorbable polyol fatty acid polyester to effect detoxification.
REFERENCES:
patent: 2893990 (1959-07-01), Hass et al.
patent: 3251827 (1966-05-01), Schnell et al.
patent: 3859318 (1975-01-01), Lesuer
patent: 4005195 (1977-01-01), Jandacek
patent: 4005196 (1977-01-01), Jandacek et al.
Jandacek Ronald J.
Volpenhein Robert A.
Brown Johnnie R.
Goldstein Steven J.
Roth Michael J.
The Procter & Gamble & Company
Yetter Jerry J.
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