Detoxified E. coli neurotoxin, preparation thereof and immunolog

Details Detoxified E. coli neurotoxin, preparation thereof and immunolog Detoxified E. coli neurotoxin, preparation thereof and immunolog

1982-03-04

1984-08-14

Hazel, Blondel

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

424 88, 260112R, A61K 39108, C07G 700

Patent

active

044656653

ABSTRACT:
Detoxified but still immunogenic E. coli neurotoxin is prepared by bringing E. coli neurotoxin into contact with glutaraldehyde in mild operative conditions, the reaction being stopped where no more than 90% of the neurotoxin are inactivated.
The obtained detoxified neurotoxin is valuable for immunizing piglets against oedema disease.

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