Determining the ability of a compound to inhibit the cyclopropan

Details Determining the ability of a compound to inhibit the cyclopropan Determining the ability of a compound to inhibit the cyclopropan

1995-06-01

1996-11-12

Jones, W. Gary

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435183, C12Q 168, C12N 900

Patent

active

055739156

ABSTRACT:
DNA and protein compositions useful for both diagnosis and design of therapeutics for treatment of tuberculosis and other mycobacterial infections. More specifically, the present invention relates to DNA and protein compositions which are responsible for the cyclopropanation of mycolic acids in M. tuberculosis and other pathogenic forms of mycobacterium. A method for determining the ability of a compound to inhibit the cyclopropanation of mycolic acids in pathogenic mycobacteria is disclosed.

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