Determining effects of psychoactive compounds on the brain using

Details Determining effects of psychoactive compounds on the brain using Determining effects of psychoactive compounds on the brain using

1995-09-01

1998-10-27

Jarvis, William R. A.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

424 161, 514322, 514356, 514649, 514651, 514724, A61K 5104, A61K 31445, A61K 3144, A61K 31135, A61K 31045

Patent

active

058274995

ABSTRACT:
A method of determining the effects of administering a psychoactive compound, such as a drug, on a patient's brain using imaging techniques with position emission tomography (PET) is disclosed. The method measures cerebral metabolism before and after administering the compound, and employs a behavioral clamp to control behavioral influences on the patient's brain after administration of the compound. The method also includes transportation of image data into standard computer space and statistical procedures for volumetrically determining areas of treatment effects.

REFERENCES:
Baxter et al, Biological Abstracts, vol. 94, Abstract No. 125570, 1992.
DeWilt et al, Biological Abstracts, vol. 90, Abstract No. 68450, 1990.
Volkow et al, Biological Abstracts, vol. 90, Abstract No. 81769, 1990.

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