Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure
Patent
1977-06-02
1979-09-11
Padgett, Benjamin R.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
Molecular bilayer structure
206569, G01N 3316, B65D 6900
Patent
active
041675568
ABSTRACT:
A process for the quantitative determination of the transcobalamins TC-I, TC-II, and TC-III in serum. The process comprises incubating the serum with radiolabeled vitamin B-12, passing the resulting mixture through adsorption means, such as a charged cellulose filter or equivalent mini-column, for TC-II at a pH of about 8.5, adsorbing the remaining TC-I and TC-II components on a DEAE-cellulose type adsorbent, selectively desorbing the TC-III component with monopotassium phosphate solution of about 0.05 M and pH of about 4.6, and determining the radioactivity of each of the three transcobalamin fractions to indicate the individual and total unsaturated vitamin B-12 binding capacity of the three transcobalamins in the serum sample tested.
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Grossowicz Nathan
Rachmilewitz Bracha
Selhub Jacob
Klawitter Andrew L.
Nucker Christine M.
Padgett Benjamin R.
Yissum Research Development Company of the Hebrew University of
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