Determination of plasma total and unbound bilirubin using...

Chemistry: analytical and immunological testing – Heterocyclic carbon compound – Hetero-n

Reexamination Certificate

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C436S063000, C436S174000, C436S180000, C422S068100, C422S081000, C422S082000, C422S105000

Reexamination Certificate

active

07416896

ABSTRACT:
A method for determining total and bound plasma bilirubin. The method utilizes zone fluidics to enable accurate determination of the bilirubin using small volumes of sample and reagents, and significantly reduces dilution errors caused by inherent changes in bilirubin-binding with sample dilution, as well as the effects of weak bilirubin-binding competitors.

REFERENCES:
patent: 4338095 (1982-07-01), Wu
patent: 4412005 (1983-10-01), Wu
patent: 5104794 (1992-04-01), Kondo et al.
patent: 6613579 (2003-09-01), Wolcott
patent: 6887429 (2005-05-01), Marshall et al.
Ahlfors et al. Clinica Chimica Acta, vol. 365, Oct. 5, 2005, pp. 78-85.

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