Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1997-11-07
2000-02-08
Brusca, John S.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 71, 536 231, 536 253, C12Q 168, G01N 3353, C07H 2100
Patent
active
060226919
ABSTRACT:
Oligonucleotides which selectively bind to target biomolecules are determined by in vitro assay of a pool of random oligonucleotides for activity against the biomolecules, followed by recovery and characterization of selected oligonucleotides. Oligonucleotides so determined may be utilized for therapeutic, diagnostic and research reagent purposes.
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Bruice Thomas W.
Lima Walter F.
Brusca John S.
ISIS Pharmaceuticals Inc.
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