Determination of nucleic acid using electrocatalytic...

Details Determination of nucleic acid using electrocatalytic... Determination of nucleic acid using electrocatalytic...

2004-09-02

2008-12-09

Aulakh, Charanjit S (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C435S006120, C422S050000, C422S068100, C546S002000

Reexamination Certificate

active

07462720

ABSTRACT:
Compositions and methods for electrochemical detection of nucleic acid are disclosed. The compositions comprise electrocatalytic intercalators that bind to double-stranded nucleic acid and oxidize nucleic acid. Methods of detecting nucleic acid in a sample comprise forming double-stranded nucleic acid that is bound by electrocatalytic intercalators wherein the intercalators catalyze oxidation of the nucleic acid at the surface of an electrode.

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Popovich, N., et al., New Srategies for Electrochemical Nucleic Acid Detection,The Electrochemical Society Interface, pp. 30-34 (2002).

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