Determination of glycosylated hemoglobin in blood

Chemistry: physical processes – Physical processes – Crystallization

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

252408, 356 39, G01N 3316, G01N 2100

Patent

active

042004357

ABSTRACT:
A method for determining glycosylated hemoglobin in blood samples which involves liberating hemoglobins from red blood cells by chemical or physical means and reacting non-glycosylated hemoglobin with an allosteric site binding substance which reacts with the allosteric binding site of non-glycosylated hemoglobin and thereby alters the distribution between allosteric forms of the hemoglobins and measuring the change. This method is useful in monitoring glucose metabolism for detecting and controlling diabetes.

REFERENCES:
patent: 3918905 (1975-11-01), Warren
patent: 3958560 (1976-05-01), March
patent: 3964865 (1976-06-01), Das
patent: 4077772 (1978-03-01), Geissler
patent: 4142858 (1979-03-01), Acuff
M. J. McDonald et al., J. Biol. Chem., 254(3), 702-707 (1979).
M. F. Perutz, Scientific American, 239(6), 92-125 (Dec. 1978).
Ruth E. Benesh et al., Advances in Protein Chemistry, vol. 28, 211-237 (1974).
H. F. Bunn et al., Science, 200, 21-27 (Apr. 1978).
M. F. Perutz et al., Biochemistry, 17(17), 3640-3652 (1978).
S. J. Edelstein, Annual Review of Biochemistry, vol. 44, 209-232 (1975).
R. G. Shulman et al., Quat. Rev. Biophysics, 8(3), 325-420 (1975).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Determination of glycosylated hemoglobin in blood does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Determination of glycosylated hemoglobin in blood, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Determination of glycosylated hemoglobin in blood will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1682685

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.