Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1992-06-10
1994-08-30
Ceperley, Mary E.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 772, 435962, 436526, 436530, 436533, 436544, 436546, 436817, 436825, G01N 33547, G01N 33548
Patent
active
053427602
ABSTRACT:
The present invention relates to the measurement of estradiol using competitive immunoassay methods. The inventors unexpectedly discovered that estrone and its derivatives conjugated to a label is a particularly effective tracer when used in conjunction with estradiol specific antibodies to determine estradiol levels in fluid samples. The present invention also utilizes 5.alpha.-dihydrotestosterone to enhance the assay performance.
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Baker Harold N.
Eng Katherine K.
Gurner William D.
Massei Michael K.
Osikowicz Eugene W.
Abbott Laboratories
Ceperley Mary E.
Wong Wean Khing
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