Determination of CK isoenzymes and CK isoforms

Details Determination of CK isoenzymes and CK isoforms Determination of CK isoenzymes and CK isoforms

1991-08-20

1994-11-29

Wax, Robert A.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 792, 435194, 436503, 436524, 436526, G01N 3353, G01N 33551, G01N 33567, C12Q 150

Patent

active

053690060

ABSTRACT:
An immunoassay for CK isoenzyme or CK isoform is provided based on capture of the CK isoenzyme or CK isoform by a specific antibody immobilized through a cleavable linker containing a disulfide bond onto a solid phase and release of the resulting antibody-CK isoenzyme or antibody-CK isoform complex by the addition of a reducing agent to cleave the disulfide bond and simultaneously activate the CK isoenzyme or CK isoform.

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