Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-03-28
2006-03-28
Ketter, James (Department: 1636)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S029000, C435S040500
Reexamination Certificate
active
07018804
ABSTRACT:
This invention provides methods to the determination of the viability of the cell by a first reagent and the phenotype of a cell by use of one or more second reagent. The first reagent is one that is detectable in viable, or living, cells even after they have been fixed such that they are no longer viable. The one or more second reagent is compatible for use in fluorescence activated cell sorting (FACS) including intracellular FACS. The invention thus provides methods of simultaneously identifying a cell as both viable and having a phenotype of interest. The invention also provides compositions for use in the disclosed methods.
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Ketter James
Orion Biosolutions, Inc.
Townsend and Townsend / and Crew LLP
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