Determination of CEA binding substance using anti-goat immunoglo

Details Determination of CEA binding substance using anti-goat immunoglo Determination of CEA binding substance using anti-goat immunoglo

1984-11-14

1988-03-22

Marantz, Sidney

Chemistry: analytical and immunological testing

Involving iga, igd, ige, or igm

436536, 436545, 436544, 436538, 436540, 436811, 436813, 436825, G01N 33053, G01N 33534, G01N 33541, G01N 33537

Patent

active

047328622

ABSTRACT:
A method is disclosed for the determination of human serum factors which are specific for human carcinomata antigens, in which method the serum of a patient with a carcinoma is incubated with CEA that has been radioactively labeled and anti-goat immunoglobulin serum in toto or depleted of the cross-reaction capacity for human IgA, IgG and IgM is added, then the whole mass is incubated and centrifugated, the supernatant is decanted and the precipitate is counted with a gamma counter. These specific serum factors are employed as a marker of primitive tumoral forms.

REFERENCES:
patent: 4178359 (1979-12-01), Mondabaugh et al.
patent: 4299815 (1981-11-01), Hansen et al.
K. Kapsopoulou-Dominos & F. A. Anderer, "An Approach to the Routine Estimation of Circulating Carcinoembryonic antigen Immune Complexes in Patients with Carcinomata of the Gastrointestinal Tract"-Clin. Exp. Immunol (1979) 37, 25-32.
J. M. MacSween, "The Antigenicity of Carcinoembryonic Antigen", Int. J. Cancer 15, 246-252 (1975).
Phil Gold and S. O. Friedman, "Demonstration of Tumor-Specific Antigens in Human Colonic Carcinomata by Immunological Tolerance and Absorption Techniques", J. Exp. Med. 121, 439 (1965).
P. LoGerfo et al, "Absence of Circulating Antibodies to Carcinoembryonic Antigen in Patients with Gastrointestinal Malignancies", Int. J. Cancer: 9, 344-348 (1972).
E. Collatz et al, "Further Investigations of Circulating Antibodies in Colon Cancer Patients: On the Autoantigenicity of the Carcinoembryonic Antigen", Int. J. Cancer 8, 298-303 (1971).
K. Kapsopoulou-Dominos et al, "Circulating Carcinoembryonic Antigen Immune Complexes in Sera of Patients with Carcinomata of the Gastrointestinal Tract", Clin. Exp. Immunol (1979), 35, 190-95.
J. M. Gold et al, "Human Anti-CEA Antibodies Detected by Radioimmunoelectrophoresis", Nature New Biology 238, 60-62 (1972).
G. M. Mavligit et al, "Colorectal Carcinoma", 0008-543X/0701/0146, American Cancer Society.

Affiliated with

Also associated with

Rating

Determination of CEA binding substance using anti-goat immunoglo does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Determination of CEA binding substance using anti-goat immunoglo, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Determination of CEA binding substance using anti-goat immunoglo will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-441974