Determination of Alzheimer's disease risk using apolipoprotein E

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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435 71, 435 4, 435 912, 435 9152, 536 235, 536 2431, 536 2433, 530350, 935 9, 935 78, C07H 2104, C12Q 168, C12P 1934, G01N 3353

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057732205

ABSTRACT:
The invention is directed to a method for screening for the risk of developing Alzheimer's disease (AD) in a subject by detecting the presence or absence of the APOE4 allele and the presence or absence of the ACT alleles which modify the risk of AD associated with the APOE4 allele. The invention offers a non-invasive method to identify individuals at high risk for the development of AD.

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