Chemistry: analytical and immunological testing – Metal or metal containing – Present in biological fluids
Patent
1984-07-27
1987-01-27
Richman, Barry S.
Chemistry: analytical and immunological testing
Metal or metal containing
Present in biological fluids
436 79, 436164, 436178, G01N 118, G01N 2175, G01N 3320, G01N 3350
Patent
active
046394249
ABSTRACT:
A method for determining the alkali metal content of a liquid such as protein-containing liquids wherein a liquid containing alkali metal cation is contacted with a monocyclic crown ether capable of forming a complex with the alkali metal cation in a substantially inert solvent and an anionic dye, is disclosed. The alkali metal forms a complex with the ether and the dye in the solvent, the presence of which is a measure of the alkali metal content of the liquid.
REFERENCES:
Sumiyoshi et al., Talanta, vol. 24, pp. 763-765, 1977.
Jawaid et al., Talanta, vol. 25, pp. 91-95, 1978.
Nakamura et al., Talanta, vol. 26, pp. 921-927, 1979.
Sanz-Medel et al., Talanta, vol. 28, pp. 425-430, 1981.
Takagi et al., Analytica Chimica Acta, vol. 126, pp. 185-190, 1981.
Marcus et al., J. Physical Chemistry, vol. 82, No. 11, pp. 1246-1254, 1978.
Nakamura et al., Anal. Chem., vol. 52, pp. 1668-1671, 1980.
Abbott Laboratories
Corneglio Donald L.
Delahunty C. M.
Richman Barry S.
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