Drug – bio-affecting and body treating compositions – Dentifrices – Oxygen or chlorine releasing compound containing
Patent
1997-09-04
1998-06-02
Anthony, Joseph D.
Drug, bio-affecting and body treating compositions
Dentifrices
Oxygen or chlorine releasing compound containing
424 49, 25218627, 25218638, 25218643, 510117, 510312, 510375, 510376, 510466, A61K 730, C01B 1506, C01B 1512
Patent
active
057595232
DESCRIPTION:
BRIEF SUMMARY
This application is a 371 of PCT/US95/16673 filed Dec. 12, 1995.
TECHNICAL FIELD
The present invention relates to cleansing compositions and especially to compositions for use in cleansing dentures and the like. In particular, the invention relates to denture cleansing compositions having enhanced antiplaque activity together with excellent denture cleansing performance, appearance, physical and dissolution characteristics, anti-bacterial efficacy and in-use performance characteristics.
BACKGROUND
Effervescent tablets and powders for cleansing dentures and the like are well known in the art. The aim of a denture cleanser product is to clean the denture as fully and as quickly as possible and especially to remove the accumulation of plaque, mucilaginous and bacterial deposits which collect while the denture is being worn. To wear a denture which has not been completely cleaned of plaque and bacterial deposits is not only unhygenic but can also within a short space of time result in a detrimental effect on the mucous membrane. Moreover bacterial deposits can lead to so-called bacterial corrosion of the plastics material used to produce the denture with consequent color-change and malodor-formation.
It is known to include silicones in dentifrice compositions, allegedly to coat the teeth and prevent cavities and staining. For instance, GB-A-689,679 discloses a mouthwash containing an organopolysiloxane for preventing adhesion of, or for removing tars, stains, tartar and food particles from the teeth.
U.S. Pat. No. 2,806,814 discloses dental preparations including, in combination, a higher aliphatic acyl amide of an amino carboxylic acid compound as an active and a silicone compound. The patent notes that silicone compounds have been proposed for prevention of adhesion or to facilitate the removal of tars, stains, tartar and the like from teeth.
The silicone compound is said to act as a synergist in improving the antibacterial and acid inhibiting activity of the active ingredient. Dimethyl polysiloxanes are said to be particularly effective.
U.S. Pat. No. 3624120 discloses quaternary ammonium salts of cyclic siloxane polymers for use as cationic surfactants, bactericides and as anticariogenic agents.
Dentures of course are generally made of a plastics material such as acrylic and the problem of preventing plaque accumulation or of removing plaque from dentures is therefore fundamentally different from the problem of plaque prevention and removal from dental enamal.
Accordingly, the present invention provides a denture cleanser having improved efficacy on plaque, mucilaginous and bacterial deposits and which at the same time provides excellent denture cleansing performance, appearance, physical characteristics, dissolution and in-use performance characteristics.
SUMMARY OF THE INVENTION
According to a first aspect of the invention, there is provided a denture cleansing composition comprising an inorganic persalt bleaching agent, an effervescence generator and a dimethicone copolyol selected from alkyl- and alkoxy-dimethicone copolyols having the formula (I): ##STR1## wherein X is selected from hydrogen, alkyl, alkoxy and acyl groups having from about 1 to about 16 carbon atoms, Y is selected from alkyl and alkoxy groups having from about 8 to about 22 carbon atoms, n is from about 0 to about 200, m is from about 1 to about 40, q is from about 1 to about 100, the molecular weight of the residue (C.sub.2 H.sub.4 O--).sub.x (C.sub.3 H.sub.6 O--).sub.y X is from about 50 to about 2000, preferably from about 250 to about 1000 and x and y are such that the weight ratio of oxyethylene:oxypropylene is from about 100:0 to about 0:100, preferably from about 100:0 to about 20:80. The present invention also relates to the use of the defined dimethicone copolyol as antiplaque agent in denture cleansing compositions
All percentages and ratios herein are by weight of total composition, unless otherwise indicated.
The cleansing compositions of the invention thus comprise three essential components, a bleaching agent, a
REFERENCES:
patent: 3607759 (1971-09-01), Barth
patent: 3624120 (1971-11-01), Yetter
patent: 4155868 (1979-05-01), Kaplan et al.
patent: 5055305 (1991-10-01), Young
patent: 5302375 (1994-04-01), Viscio
patent: 5310563 (1994-05-01), Curtis et al.
patent: 5403578 (1995-04-01), Gordon
Hughes Iain Allan
Ryan Elizabeth Mary
White Christopher David
Anthony Joseph D.
Clemo Nick G.
Hentz Mary Catherine
Mohl Douglas C.
The Procter & Gamble & Company
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