Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2011-06-28
2011-06-28
Cheu, Jacob (Department: 1641)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007200, C436S518000
Reexamination Certificate
active
07968302
ABSTRACT:
A method and a test for detecting coagulation activation, in particular when it is responsible for thromboembolic venous diseases; employs assaying D-dimers and assaying the soluble fibrin produced during a fibrinolysis process activated in a blood sample. The method of the invention pertains to comparing the level of D-dimers corresponding to degradation of soluble fibrin and the level of D-dimers of the sample with normal threshold values. The test of the invention may also be used to determine whether anti-coagulation is sufficient in a patient.
REFERENCES:
patent: 5114845 (1992-05-01), Randby
patent: 5206140 (1993-04-01), Marder et al.
patent: 0347933 (1989-12-01), None
patent: 02/18628 (2002-03-01), None
Scott K. Brimble et al., “Evaluation of the Combination of a Bedside D-Dimer Assay and Enzyme-Linked Immunosorbent Soluble Fibrin Assay in Patients with Suspected Venous Thromboembolism”, Thrombosis Research, Nov. 1, 1997, pp. 291-297, vol. 88, No. 3, Elsevier Science Ltd., USA.
Satoshi Ota et al., “Diagnosis of Deep Vein Thrombosis by Plasma-Soluble Fibrin or D-Dimer”, American Journal of Hematology, Aug. 2005, pp. 274-280, vol. 79, No. 4, Wiley-Liss, Inc.
Y.S. Arkel et al., “The use of coagulation activation markers (soluble fibrin polymer, TpPTM, prothrombin fragment 1.2, thrombin-antithrombin, and D-dimer) in the assessment of hypercoagulability in patients with inherited and acquired prothrombotic disorders”, Blood Coagulation and Fibrinolysis, Apr. 2002, pp. 199-205, vol. 13, No. 3, Lippincott Williams & Wilkins.
French Preliminary Search Report and Written Opinion, mailed Dec. 12, 2006 in corresponding French Patent Application No. FR 0604072.
International Search Report dated Sep. 28, 2007, in PCT application.
Mirshahi Bibi Shah Soltan
Soria Jeannette
Assistance Publique - Hopitaux de Paris
Cheu Jacob
Diagnostica Stago
Young & Thompson
LandOfFree
Detection of venous thromboembolic diseases by measurement... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Detection of venous thromboembolic diseases by measurement..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Detection of venous thromboembolic diseases by measurement... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2701171